| Play | Key Line | Modern Text | Original Text |
| Antony and Cleopatra | AC III.ii.57 | That year indeed he was troubled with a rheum. | That year indeed, he was trobled with a rheume, |
| The Comedy of Errors | CE III.ii.135 | stood in her chin, by the salt rheum that ran between | stood in her chin by the salt rheume that ranne betweene |
| Coriolanus | Cor V.vi.46 | At a few drops of women's rheum, which are | At a few drops of Womens rhewme, which are |
| Hamlet | Ham II.ii.504 | With bisson rheum; a clout upon that head | With Bisson Rheume: A clout about that head, |
| Henry V | H5 III.v.52 | The Alps doth spit and void his rheum upon! | The Alpes doth spit, and void his rhewme vpon. |
| King John | KJ III.i.22 | Why holds thine eye that lamentable rheum, | Why holdes thine eie that lamentable rhewme, |
| King John | KJ IV.i.33 | Read here, young Arthur. (aside) How now, foolish rheum! | Reade heere yong Arthnr. How now foolish rheume? |
| King John | KJ IV.iii.108 | For villainy is not without such rheum, | For villanie is not without such rheume, |
| Measure for Measure | MM III.i.31 | Do curse the gout, serpigo, and the rheum | Do curse the Gowt, Sapego, and the Rheume |
| The Merchant of Venice | MV I.iii.114 | You, that did void your rheum upon my beard | You that did voide your rume vpon my beard, |
| Much Ado About Nothing | MA V.ii.75 | quarter in rheum. Therefore is it most expedient for the | quarter in rhewme, therfore is it most expedient for the |
| Othello | Oth III.iv.51 | I have a salt and sorry rheum offends me; | I haue a salt and sorry Rhewme offends me: |
| Richard II | R2 I.iv.8 | Awaked the sleeping rheum, and so by chance | Awak'd the sleepie rhewme, and so by chance |
| Troilus and Cressida | TC V.iii.104 | o' these days; and I have rheum in mine eyes too, and | o'th's dayes: and I haue a rheume in mine eyes too; and |
| The Two Noble Kinsmen | TNK V.iv.8 | The gout and rheum, that in lag hours attend | The Gowt and Rheume, that in lag howres attend |