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vigour (n.)  power, efficacy, effect
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Cym [Queen to Cornelius, of his drugs] To try the vigour of them
Ham I.v.68 [Ghost to Hamlet, of the poison] And with a sudden vigour it doth posset
MM II.ii.184 [Angelo alone] Never could the strumpet / With all her double vigour ... / Once stir my temper
Tem I.ii.486 [Prospero to Ferdinand] Thy nerves are in their infancy again, / And have no vigour in them
Ven 953 [Venus as if to death] Now Nature cares not for thy mortal vigour